Clonidine for the prevention of emergence agitation in young children: efficacy and recovery profile

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Clonidine for the prevention of emergence agitation in young children: efficacy and recovery profile.

BACKGROUND Emergence agitation (EA) is a common postoperative problem in young children who have received sevoflurane and isoflurane for general anesthesia. This randomized, double-blinded study evaluated the efficacy of intraoperative clonidine in reducing EA, and describes its recovery profile. METHODS With Institutional Review Board approval and informed consent, children undergoing brief,...

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The prevention of emergence agitation with tropisetron or clonidine after sevoflurane anesthesia in small children undergoing adenoidectomy.

Postoperative agitation is a common problem after sevoflurane anesthesia in children. In the present study, we evaluated if tropisetron or clonidine could reduce the incidence of postoperative agitation after day case adenoidectomy in small children. We included 75 unpremedicated children aged 1-7 yr who were randomly assigned to receive either placebo, tropisetron (0.1 mg/kg) or clonidine (1.5...

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PROPOFOL THIOPENTAL MIDAZOLAM CLONIDINE Prevention of Emergence Agitation Treatment of Emergence Agitation OPIOIDS NOTHING OTHER RESTRAINT PARENTS MIDAZOLAM OPIOIDS CLONIDINE PROPOFOL

Editor—Emergence agitation is a topic of clinical interest since the introduction of sevoflurane and desflurane, and it remains oneoftheunansweredquestionsforthepaediatricanaesthetist. The incidence is reported to be between 10% and 80% depending on definition and evaluation scale used. Emergence agitation, although self-limited, may require physical restraint and is a considerable source of di...

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Emergence agitation in children

unclear. Interestingly, the authors made a behavioural assessment within 1 week and found no functional deficits, but the tests used lacked discrimination of motor or sensory deficits, paraesthesia, or painful neuropathies Therefore, functional data should be interpreted with caution. Objective evaluation of nerve injury, for example, myelin damage, is missing. Behavioural assessment is challen...

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Oral clonidine vs midazolam in the prevention of sevoflurane-induced agitation in children.

BACKGROUND This randomized, double-blind study tested the hypothesis that, in comparison with midazolam, premedication with oral clonidine reduces the incidence of emergence agitation in preschool children anaesthetized with sevoflurane. METHODS Sixty-eight ASA I-II children undergoing circumcision were randomized into three groups to receive different oral premedication given 30 min before a...

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ژورنال

عنوان ژورنال: Pediatric Anesthesia

سال: 2006

ISSN: 1155-5645,1460-9592

DOI: 10.1111/j.1460-9592.2006.01818.x